S. Sadegh

Latest

• Lacking mechanistic disease definitions and corresponding association data hamper progress in network medicine and beyond
• Network-based approaches for modeling disease regulation and progression
• Robust disease module mining via enumeration of diverse prize-collecting Steiner trees
• Network medicine for disease module identification and drug repurposing with the NeDRex platform
• Lessons from the COVID-19 pandemic for advancing computational drug repurposing strategies
• NOX5-induced uncoupling of endothelial NO synthase is a causal mechanism and theragnostic target of an age-related hypertension endotype
• Exploring the SARS-CoV-2 virus-host-drug interactome for drug repurposing