J. Baumbach

Latest

• Network medicine-based epistasis detection in complex diseases: ready for quantum computing
• The publication titled 'Inference of differential gene regulatory networks using boosted differential trees' now published in Bioinformatics Advances.
• On the limits of 16S rRNA gene-based metagenome prediction and functional profiling
• Inference of differential gene regulatory networks using boosted differential trees
• Alternative splicing impacts microRNA regulation within coding regions
• Alternative splicing analysis benchmark with DICAST
• Lacking mechanistic disease definitions and corresponding association data hamper progress in network medicine and beyond
• Network-based approaches for modeling disease regulation and progression
• Systematic analysis of alternative splicing in time course data using Spycone
• The limits of molecular signatures for pancreatic ductal adenocarcinoma subtyping
• Hypothesis of a potential BrainBiota and its relation to CNS autoimmune inflammation
• Tumour cell budding and spread through air spaces in squamous cell carcinoma of the lung - Determination and validation of optimal prognostic cut-offs
• Systematic analysis of alternative splicing in time course data using Spycone
• sPLINK: a hybrid federated tool as a robust alternative to meta-analysis in genome-wide association studies
• Privacy-Preserving Artificial Intelligence Techniques in Biomedicine
• Robust disease module mining via enumeration of diverse prize-collecting Steiner trees
• Alternative splicing analysis benchmark with DICAST
• The Limits of Molecular Signatures for Pancreatic Ductal Adenocarcinoma Subtyping
• Functional enrichment of alternative splicing events with NEASE reveals insights into tissue identity and diseases
• Network medicine for disease module identification and drug repurposing with the NeDRex platform
• Long-term instability of the intestinal microbiome is associated with metabolic liver disease, low microbiota diversity, diabetes mellitus and impaired exocrine pancreatic function
• The AIMe registry for artificial intelligence in biomedical research
• ASimulatoR: splice-aware RNA-Seq data simulation
• Network analysis methods for studying microbial communities: A mini review
• Enabling single-cell trajectory network enrichment
• Lessons from the COVID-19 pandemic for advancing computational drug repurposing strategies
• BiCoN: Network-constrained biclustering of patients and omics data
• NOX5-induced uncoupling of endothelial NO synthase is a causal mechanism and theragnostic target of an age-related hypertension endotype
• DIGGER: exploring the functional role of alternative splicing in protein interactions
• sPLINK: A Federated, Privacy-Preserving Tool as a Robust Alternative to Meta-Analysis in Genome-Wide Association Studies
• Multi-Omics Analysis in a Network Context (in "Reference Module in Biomedical Sciences")
• Exploring the SARS-CoV-2 virus-host-drug interactome for drug repurposing
• EpiGEN: an epistasis simulation pipeline
• Comparative single-cell trajectory network enrichment identifies pseudo-temporal systems biology patterns in hematopoiesis and CD8 T-cell development
• BiCoN: Network-constrained biclustering of patients and omics data